Biometrical Letters Vol. 49(2), 2012, pp. 81-94


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THE EXTREME VALUE BIRNBAUM-SAUNDERS MODEL, ITS MOMENTS AND AN APPLICATION IN BIOMETRY

M. Ivette Gomes1, Marta Ferreira2, Victor Leiva3

1Universidade de Lisboa, DEIO, CEAUL and FCUL, Portugal e-mail: ivette.gomes@fc.ul.pt
2Departamento de Matemática, Universidade do Minho, Portugal
3Departamento de Estadística, Universidad de Valparaíso, Chile


The Birnbaum-Saunders (BS) model is a life distribution that has been widely studied and applied. Recently, a new version of the BS distribution based on extreme value theory has been introduced, named the extreme value Birnbaum-Saunders (EVBS) distribution. In this article we provide some further details on the EVBS models that can be useful as a supplement to the existing results. We use these models to analyse real survival time data for patients treated with alkylating agents for multiple myeloma. This analysis allow us to show the adequacy of these new statistical distributions and identify them as models useful for medical practitioners in order to predict survival times for such patients and evaluate changes in their treatment dose.


extreme value theory, parametric modelling, survival data